Quellen

Nachfolgend ist die verwendete Literatur kapitelweise aufgeführt. Klicken Sie auf einen Kapitelnamen, um die Liste aufzublättern und zu schließen.

Einleitung

Rozenblit L & Keil F (2002) The misunderstood limits of folk science: An illusion of explanatory depth. Cognitive Science 26:521-562, doi: 10.1207/s15516709cog2605_1
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Nishimasu H, Ran FA et al. (2014) Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA. Cell 156:935-949, doi: 10.1016/j.cell.2014.02.001
Wünschiers R (2019) Generation Gen-Schere: Wie begegnen wir der gentechnologischen Revolution. Springer, Berlin, ISBN 978-3662590478, doi: 10.1038/s41562-018-0520-3
Robinson T (2017) Genetik für Dummies. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, ISBN 978-3-527-71417-9
Fernbach PM, Light N et al. (2019) Extreme opponents of genetically modified foods know the least but think they know the most. Nat Hum Behav 3:251-256, doi: 10.1038/s41562-018-0520-3
Küntzel K (2019) Nachhaltig & ökologisch Leben für Dummies. John Wiley & Sons, Incorporated, Newark, ISBN 978-3-527-82178-5
NASA, Images on the golden record. Zugegriffen unter Internetlink, zugegriffen am 19/01/21

Kapitel 1: Die Welt der Gene

Chargaff E (2003) Stimmen im Labyrinth: Drei Dialoge über die Natur und ihre Erforschung. Klett-Cotta, Stuttgart, ISBN 978-3608935806
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— (2014), Goldmedaille für 4,7 Millionen Dollar versilbert. Zugegriffen unter Internetlink, zugegriffen am 30/11/20
— (2019), Nobelpreisträger Watson verliert Ehrentitel wegen rassistischer Äußerungen. Zugegriffen unter Internetlink, zugegriffen am 30/11/20
Sender R, Fuchs S & Milo R (2016) Revised Estimates for the Number of Human and Bacteria Cells in the Body. PLOS Biology 14:e1002533, doi: 10.1371/journal.pbio.1002533
Sender R & Milo R (2021) The distribution of cellular turnover in the human body. Nat Med 27:45-48, doi: 10.1038/s41591-020-01182-9
Preston BD, Albertson TM & Herr AJ (2010) DNA replication fidelity and cancer. Seminars in Cancer Biology 20:281-293, doi: 10.1016/j.semcancer.2010.10.009
de Vries H (1901) Die Mutationstheorie. Versuche und Beobachtungen über die Entstehung von Arten im Pflanzenreich. Veit & Comp., doi: 10.5962/bhl.title.11336
McClintock B (1931) The Order of the Genes C, Sh and Wx in Zea Mays with Reference to a Cytologically Known Point in the Chromosome. Proc Natl Acad Sci USA 17:485-491, doi: 10.1073/pnas.17.8.485
Creighton HB & McClintock B (1931) A Correlation of Cytological and Genetical Crossing-Over in Zea Mays. Proc Natl Acad Sci USA 17:492-497, doi: 10.1073/pnas.17.8.492
Wolpert L, Ghysen A & García-Bellido A (1998) Debatable issues. The International journal of developmental biology 42:511-518
Mendel G (1866) Versuche über Pflanzen-Hybriden. Verhandlungen des Naturforschenden Vereins zu Brünn 4:3-47, doi: 10.5962/bhl.title.61004
Bateson W (1902) Mendel's principles of heredity: A defence. University Press, doi: 10.5962/bhl.title.46238
Brem G (Editor) (2017) 150 Jahre Mendelsche Regeln: Vom Erbsenzählen zum Gen-Editieren, Nova Acta Leopoldina, Deutsche Akademie der Naturforscher Leopoldina - Nationale Akademie der Wissenschaften: Wissenschaftliche Verlagsgesellschaft, ISBN 978-3-8047-3703-7
Johannsen W (1909) Elemente der exakten Erblichkeitslehre. Verlag von Gustav Fischer, Jena, doi: 10.5962/bhl.title.1060
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Dolgin E (2017) The most popular genes in the human genome. Nature 551:427-431, doi: 10.1038/d41586-017-07291-9
Armstrong S (2014) P53: The gene that cracked the cancer code. Bloomsbury Sigma, London, ISBN 978-1-4729-1053-0
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Belyi VA, Ak P et al. (2009) The Origins and Evolution of the p53 Family of Genes. Cold Spring Harbor Perspectives in Biology 2:a001198-a001198, doi: 10.1101/cshperspect.a001198
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Deuker MM, Lewis KN et al. (2020) Unprovoked Stabilization and Nuclear Accumulation of the Naked Mole-Rat p53 Protein. Scientific Reports 10, doi: 10.1038/s41598-020-64009-0
Goethe J (2016) Gedichte: Ausgabe letzter Hand 1827. Hofenberg, ISBN 978-3-8430-1760-2
Pozhitkov AE, Neme R et al. (2017) Tracing the dynamics of gene transcripts after organismal death. Open Biology 7:160267, doi: 10.1098/rsob.160267
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Rutherford A, Dna's twist to the right is not to be meddled with, so let's lose the lefties. Zugegriffen unter Internetlink, zugegriffen am 30/11/20
Schneider T, The left handed dna hall of fame. Zugegriffen unter Internetlink, zugegriffen am 30/11/20
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Hou W (2020) Characterization of codon usage pattern in SARS-CoV-2. Virol J 17, doi: 10.1186/s12985-020-01395-x
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Chang JC & Kan YW (1979) Beta zero thalassemia, a nonsense mutation in man. Proc Natl Acad Sci USA 76:2886-2889, doi: 10.1073/pnas.76.6.2886
Hamosh A, King T et al. (1992) Cystic fibrosis patients bearing both the common missense mutation Gly>Asp at codon 551 and the delta F508 mutation are clinically indistinguishable from delta F508 homozygotes, except for decreased risk of meconium ileus. American journal of human genetics 51 2:245-50
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Vilarrasa-Blasi R, Soler-Vila P et al. (2021) Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation. Nat Commun 12, doi: 10.1038/s41467-020-20849-y

Kapitel 2: Von der Vererbung zur quantitativen Genetik

Szabó A (2017) Ursprung des Begriffs Genetik und seine Verwendung vor und nach Mendel. Nova Acta Leopoldina 65-79
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Galton F (1886) Regression Towards Mediocrity in Hereditary Stature. The Journal of the Anthropological Institute of Great Britain and Ireland 15:246, doi: 10.2307/2841583
Wikipedia, Regression toward the mean. Zugegriffen unter Internetlink, zugegriffen am 22/03/21
Boyle EA, Li YI & Pritchard JK (2017) An Expanded View of Complex Traits: From Polygenic to Omnigenic. Cell 169:1177-1186, doi: 10.1016/j.cell.2017.05.038
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Kapitel 3: Vom Gen übers Genom zum Ich

Slonim N, Bilu Y et al. (2021) An autonomous debating system. Nature 591:379-384, doi: 10.1038/s41586-021-03215-w
Rebout N, Lone JC et al. (2021) Measuring complexity in organisms and organizations. R Soc open sci 8, doi: 10.1098/rsos.200895
Waring M & Britten RJ (1966) Nucleotide Sequence Repetition: A Rapidly Reassociating Fraction of Mouse DNA. Science 154:791-794, doi: 10.1126/science.154.3750.791
Peterson DG, Wessler SR & Paterson AH (2002) Efficient capture of unique sequences from eukaryotic genomes. Trends in Genetics 18:547-550, doi: 10.1016/s0168-9525(02)02764-6
Van Valen L (1973) A new evolutionary law. Evolutionary theory 1:1-30
Carroll L (1998) Alice hinter den Spiegeln. Insel-Verlag, Frankfurt am Main, ISBN 9783458317975
Weber-Lehmann J, Schilling E et al. (2014) Finding the needle in the haystack: Differentiating "identical" twins in paternity testing and forensics by ultra-deep next generation sequencing. Forensic Science International: Genetics 9:42-46, doi: 10.1016/j.fsigen.2013.10.015
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Carretero-Paulet L, Librado P et al. (2015) High Gene Family Turnover Rates and Gene Space Adaptation in the Compact Genome of the Carnivorous Plant Utricularia gibba. Molecular Biology and Evolution 32:1284-1295, doi: 10.1093/molbev/msv020
Bodea GO, McKelvey EGZ & Faulkner GJ (2018) Retrotransposon-induced mosaicism in the neural genome. Open Biol 8:180074, doi: 10.1098/rsob.180074
Locke DP, Hillier LW et al. (2011) Comparative and demographic analysis of orang-utan genomes. Nature 469:529-533, doi: 10.1038/nature09687
Payer LM, Steranka JP et al. (2017) Structural variants caused by Alu insertions are associated with risks for many human diseases. Proc Natl Acad Sci USA 114:E3984-E3992, doi: 10.1073/pnas.1704117114
Comas D, Plaza S et al. (2001) Recent Insertion of an Alu Element Within a Polymorphic Human-Specific Alu Insertion. Molecular Biology and Evolution 18:85-88, doi: 10.1093/oxfordjournals.molbev.a003722
Cordaux R & Batzer MA (2009) The impact of retrotransposons on human genome evolution. Nat Rev Genet 10:691-703, doi: 10.1038/nrg2640
Touchon M, Hoede C et al. (2009) Organised Genome Dynamics in the Escherichia coli Species Results in Highly Diverse Adaptive Paths. PLoS Genetics 5:e1000344, doi: 10.1371/journal.pgen.1000344
Stokes HW & Gillings MR (2011) Gene flow, mobile genetic elements and the recruitment of antibiotic resistance genes into Gram-negative pathogens. FEMS Microbiology Reviews 35:790-819, doi: 10.1111/j.1574-6976.2011.00273.x
Stegemann S & Bock R (2009) Exchange of Genetic Material Between Cells in Plant Tissue Grafts. Science 324:649-651, doi: 10.1126/science.1170397
Sjölund M, Bonnedahl J et al. (2008) Dissemination of Multidrug-Resistant Bacteria into the Arctic. Emerg Infect Dis 14:70-72, doi: 10.3201/eid1401.070704
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Clemente JC, Pehrsson EC et al. (2015) The microbiome of uncontacted Amerindians. Sci Adv 1:e1500183, doi: 10.1126/sciadv.1500183
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Miga KH, Koren S et al. (2020) Telomere-to-telomere assembly of a complete human X chromosome. Nature 585:79-84, doi: 10.1038/s41586-020-2547-7
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Kapitel 4: Safety First: Gentechnik und Gesetze

Berg P, Baltimore D et al. (1974) Potential Biohazards of Recombinant DNA Molecules. Science 185:303-303, doi: 10.1126/science.185.4148.303
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Kapitel 5: Drei Gene verändern die Welt

Suttle CA (2005) Viruses in the sea. Nature 437:356-361, doi: 10.1038/nature04160
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Chang ACY & Cohen SN (1974) Genome Construction Between Bacterial Species In Vitro: Replication and Expression of Staphylococcus Plasmid Genes in Escherichia coli. Proc Natl Acad Sci USA 71:1030-1034, doi: 10.1073/pnas.71.4.1030
Pappalardo AM, Petraccioli A et al. (2019) From Fish Eggs to Fish Name: Caviar Species Discrimination by COIBar-RFLP, an Efficient Molecular Approach to Detect Fraud in the Caviar Trade. Molecules 24:2468, doi: 10.3390/molecules24132468
Ropka-Molik K, Stefaniuk-Szmukier M et al. (2019) The use of the SLC16A1 gene as a potential marker to predict race performance in Arabian horses. BMC Genetics 20, doi: 10.1186/s12863-019-0774-4
Lehman IR, Bessman MJ et al. (1958) Deoxyribonucleic acid polymerase from the extreme thermophile Thermus aquaticus. Biol Chem 233:163-170
Klenow H & Henningsen I (1970) Selective Elimination of the Exonuclease Activity of the Deoxyribonucleic Acid Polymerase from Escherichia coli B by Limited Proteolysis. Proc Natl Acad Sci USA 65:168-175, doi: 10.1073/pnas.65.1.168
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Chien A, Edgar DB & Trela JM (1976) Deoxyribonucleic acid polymerase from the extreme thermophile Thermus aquaticus. Journal of Bacteriology 127:1550-1557, doi: 10.1128/jb.127.3.1550-1557.1976
Wheeler DA, Srinivasan M et al. (2008) The complete genome of an individual by massively parallel DNA sequencing. Nature 452:872-876, doi: 10.1038/nature06884
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van der Valk T, Pečnerová, P et al. (2021) Million-year-old DNA sheds light on the genomic history of mammoths. Nature 591:265-269, doi: 10.1038/s41586-021-03224-9
Pečnerová P, del Molino DD et al. (2021) Mammuthus sp. (Early and Middle Pleistocene Mammoths). Trends in Genetics doi: 10.1016/j.tig.2021.04.006
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Wagner DL, Amini L et al. (2018) High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population. Nat Med 25:242-248, doi: 10.1038/s41591-018-0204-6
Ledford H (2020) CRISPR gene editing in human embryos wreaks chromosomal mayhem. Nature 583:17-18, doi: 10.1038/d41586-020-01906-4
Zuccaro MV, Xu J et al. (2020) Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos. Cell 183:1650-1664.e15, doi: 10.1016/j.cell.2020.10.025
Porto EM, Komor AC et al. (2020) Base editing: Advances and therapeutic opportunities. Nature Reviews Drug Discovery 19:839-859, doi: 10.1038/s41573-020-0084-6
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Kapitel 6: Bändigung des Zufalls

Mishra R (Editor) (2012) Mutagenesis. InTech, doi: 10.5772/2937
Muller HJ (1927) Artificial Transmutation of the Gene. Science 66:84-87, doi: 10.1126/science.66.1699.84
Calabrese EJ (2018) Muller's nobel prize research and peer review. Philosophy, Ethics, and Humanities in Medicine 13, doi: 10.1186/s13010-018-0066-z
Malling HV (2004) History of the science of mutagenesis from a personal perspective. Environ Mol Mutagen 44:372-386, doi: 10.1002/em.20064
Hamer L, DeZwaan TM et al. (2001) Recent advances in large-scale transposon mutagenesis. Current Opinion in Chemical Biology 5:67-73, doi: 10.1016/s1367-5931(00)00162-9
Murray MJ & Todd WA (1972) Registration of todd's mitcham peppermint 1 (reg. no. 1). Crop Sci 12:128-128, doi: 10.2135/cropsci1972.0011183x001200010056x
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Kapitel 7: Dolly war kein Clown

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Kapitel 8: Unsere DNA als Glaskugel

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Kapitel 9: Künstliche Gene und Organismen

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Kapitel 10: Künstliche Intelligenz und echte Erkenntnisse

Bycroft C, Freeman C et al. (2018) The UK Biobank resource with deep phenotyping and genomic data. Nature 562:203-209, doi: 10.1038/s41586-018-0579-z
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Kapitel 11: Gentechnik und Umweltschutz – geht das?

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Kapitel 12: Epigenetik: Darwin und Lamarck vereint

Heard E & Martienssen RA (2014) Transgenerational Epigenetic Inheritance: Myths and Mechanisms. Cell 157:95-109, doi: 10.1016/j.cell.2014.02.045
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Kapitel 13: Gentherapien

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Kapitel 14: Wie Transhumanisten uns für die Zukunft wappnen (wollen)

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Kapitel 15: Coronavirus – Wenn »negativ« positiv ist

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Arnold C (2020) Could COVID delirium bring on dementia? Nature 588:22-24, doi: 10.1038/d41586-020-03360-8
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Kapitel 16: Zehn innovative Methoden im Bereich der Bio- und Gentechnologie

Editorial (2021) Method of the year 2020: Spatially resolved transcriptomics. Nature Methods 18:1-1, doi: 10.1038/s41592-020-01042-x
— (2020) Method of the year 2019: Single-cell multimodal omics. Nature Methods 17:1-1, doi: 10.1038/s41592-019-0703-5
— (2018) Method of the year 2018: Imaging in freely behaving animals. Nature Methods 16:1-1, doi: 10.1038/s41592-018-0292-8
— (2018) Method of the year 2017: Organoids. Nature Methods 15:1-1, doi: 10.1038/nmeth.4575
— (2017) Method of the year 2016: Epitranscriptome analysis. Nature Methods 14:1-1, doi: 10.1038/nmeth.4142
Nakane T, Kotecha A et al. (2020) Single-particle cryo-EM at atomic resolution. Nature 587:152-156, doi: 10.1038/s41586-020-2829-0
Editorial (2015) Method of the year 2015. Nature Methods 13:1-1, doi: 10.1038/nmeth.3730
— (2014) Method of the year 2014. Nature Methods 12:1-1, doi: 10.1038/nmeth.3251
— (2013) Method of the year 2013. Nature Methods 11:1-1, doi: 10.1038/nmeth.2801
— (2013) Method of the year 2012. Nature Methods 10:1-1, doi: 10.1038/nmeth.2329
— (2011) Method of the year 2011. Nature Methods 9:1-1, doi: 10.1038/nmeth.1852
Sahel JA, Boulanger-Scemama E et al. (2021) Partial recovery of visual function in a blind patient after optogenetic therapy. Nature Medicine 27:1223-1229, doi: 10.1038/s41591-021-01351-4
Editorial (2010) Method of the year 2010. Nature Methods 8:1-1, doi: 10.1038/nmeth.f.321